Ayesha was born in Mumbai, Maharashtra to a Gujarati father, Nishit and a half British - half Maharashtrian mother, Faridah. She attended St. Anthony's High School. She has a younger sister named Natasha. She is also the cousin of Abdul Zafar.
Ayesha started her career with the "I am a Complan Girl!" advertising campaign and she also appeared in a music video, Falguni Pathak's Meri Chunarii Udd Udd Jaye, when she was fifteen. She then appeared in the video, Shake It Daddy when she was sixteen, which brought her to the attention of the movie industry, and a few film offers followed. She signed a contract for Socha Na Tha. However, there were delays in making Socha Na Tha so the movie Taarzan released first and was therefore her "debut" film. She won the Filmfare Best Debut Award in 2004 for her performance in Taarzan: The Wonder Car. She earned critical acclaim for her performance in Nagesh Kukunoor's Dor. She appeared in one Telugu film Super with Tollywood star Akkineni Nagarjuna.
Ayesha's latest release was Wanted costarring Salman Khan. It emerged as the one of the biggest blockbusters of 2009.
 Personal life
On 1 March 2009, Ayesha married Farhan Azmi, a restaurateur and the son of politician Abu Azmi, a Samajwadi Party leader. The couple had originally planned to marry in December 2008, but the wedding was delayed due to the 2008 Mumbai attacks.
* 2005, Filmfare Best Female Debut Award for Taarzan: The Wonder Car
* 2004, IIFA Star Debut
* 2005, Star's Sabsey Favourite Nayi Heroine
* 2007, Star Screen Award Best Actress (Critics) for Dor
* 2007, Stardust Best Supporting Actress Award for Dor
* 2007, Bengal Film Journalists' Association Awards, Best Actress for Dor
* 2007, Zee Cine Critics Award - Best Actress, tied with Gul Panag
* 2010, Best looking award for wanted
Year Film Role Notes
2004 Taarzan: The Wonder Car Priya Rakesh Kapoor Winner, Filmfare Best Female Debut Award
Dil Maange More Shagun
Socha Na Tha Aditi
2005 Shaadi No. 1 Bhavna
Super Siri Valli Telugu film
Home Delivery: Aapko... Ghar Tak Jenny
2006 Shaadi Se Pehle Rani
Yun Hota Toh Kya Hota Khushboo
2007 Salaam-e-Ishq: A Tribute To Love Gia Bakshi
Kya Love Story Hai Kajal Mehra
Fool and Final Tina
Cash Riya Special Appearance
Blood Brothers Keya Short Film
No Smoking Anjali / Annie Double Role
2008 Sunday Sehar Thapar
De Taali Amrita "Amu"
2009 8 X 10 Tasveer Sheela First Negative Role
2010 Paathshala Anjali
Ab Dilli Door Nahin Leopard Announced
Aap Ke Liye Hum
Naughty @ Forty